Ctrp family: linking immunity to metabolism
WebMar 16, 2016 · Recent studies have shown that the CTRP family of proteins, paralogs of adiponectin, play a crucial role in the regulation of systemic metabolism and innate immunity [18,19]. CTRP-1 to CTRP-15 show remarkable similarities in their structural and biochemical properties compared to adiponectin [18]. WebSep 4, 2024 · This family, originally identified by Lodish and coworkers, is a highly conserved family consisting of secreted proteins that were cloned on the basis of an adiponectin homology sequence.1Up to now, 15 members have been identified in CTRP superfamily (CTRP1–CTRP15) (Figure 1).
Ctrp family: linking immunity to metabolism
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WebJul 28, 2015 · While structurally related to the other 15 members of the CTRP family, CTRP3 emerges as a novel adipokine with potential functions in the regulation of … WebJul 23, 2024 · The gut microbiome plays important roles in host immunity, metabolism, and the production of numerous compounds that influence the host ... 21. Schaffler A, Buechler C. CTRP Family: Linking Immunity to Metabolism. Trends Endocrinol Metab (2012) 23:194–204. doi: 10.1016/j.tem.2011.12.003.
WebApr 1, 2012 · The function and mechanism of CTRP-3 in adipocytes and monocytes are probed and it is shown that it acts as an endogenous antagonist of the toll-like receptor … WebMay 16, 2024 · CTRP9 is one of the adiponectin paralog belonging to the CTRP family, and it is expressed predominantly in adipose tissues, skeletal muscles, mammary glands, and heart. 3 It plays beneficial roles in the regulation of inflammation, oxidative stress, glucose metabolism, and vascular function as an adipocytokine through the adiponectin …
WebIt is well known that infectious and inflammatory diseases such as sepsis and severe inflammatory response syndrome are accompanied by metabolic alterations such as insulin resistance. Conversely, metabolic diseases such as visceral obesity and type 2 diabetes are characterized by high levels of proinflammatory cytokines. Metabolism and immunity … WebJan 17, 2012 · Search worldwide, life-sciences literature Search. Advanced Search Coronavirus articles and preprints Search examples: "breast cancer" Smith J
WebJul 22, 2016 · Shareable Link. Use the link below to share a full-text version of this article with your friends and colleagues. ... as the least known member of the CTRP family, CTRP8, can effectively target and activate RXFP1 receptors. ... but their important regulatory functions in metabolism, immune defence and, more recently, cancer is …
WebJul 1, 2016 · CTRP family: linking immunity to metabolism Trends Endocrinol. Metab. TEM (2012) View more references Cited by (38) CTRP1: A novel player in cardiovascular and metabolic diseases 2024, Cytokine Show abstract C1q/TNF-related Protein 1, a Multifunctional Adipokine: An Overview of Current Data 2024, American Journal of the … date picker in powerappsWebNov 22, 2024 · In recent years, some CTRP family proteins, such as CTRP5, CTRP6, and CTRP15, have been found to be associated with metabolic disorders, but there are very few reports about CTRP7 and its ... biznews youtube channelWebCTRP family: linking immunity to metabolism It is well known that infectious and inflammatory diseases such as sepsis and severe inflammatory response syndrome are accompanied by metabolic alterations such as insulin resistance. Conversely, metabolic … biznews.comWebFeb 4, 2024 · CTRPs are a group of fifteen proteins with a role similar to that of adiponectin in metabolism (Table 1) [ 7 ]. CTRPs contain four distinct domains, which include a short variable domain, a C-terminal C1q globular domain, a collagenous domain and an N-terminal signal peptide (Fig. 1) [ 7 ]. biznex holdingWebNov 23, 2024 · To characterize hepatic metabolism in fasted Ctrp3 KO mice, I further analyzed metabolomic profiles in the liver. ... Schäffler A, Buechler C (2012) CTRP family: linking immunity to metabolism. Trends Endocrinol Metab 23:194–204. Article Google Scholar Seldin MM, Tan SY, Wong GW (2014) Metabolic function of the CTRP family of … biz nf editing websiteWebTo date, 15 additional CTRP family members have been identified that might also play a role in metabolism and immunity. This review … biznext indiaWebApr 1, 2012 · The term CTRP, originally introduced by Harvey Lodish and coworkers, describes a new family of secreted proteins that were cloned on the basis of sequence … biznews south africa